abstract：OBJECTIVES:Some studies find a relationship between certain personality traits, as impulsivity or sensation seeking, and caffeine consumption, but these studies do not consider the potential confounding effect of smoking on caffeine intake, a co-occurrence that has been well demonstrated in epidemiological and clinical...

journal_title：Progress in neuro-psychopharmacology & biological psychiatry

authors： Gurpegui M,Jurado D,Luna JD,Fernández-Molina C,Moreno-Abril O,Gálvez R

更新日期：2007-06-30 00:00:00

abstract：:Autism (MIM 209850) is a neurodevelopmental disorder characterized by difficulties with verbal and non-verbal communication, impairments in reciprocal social interactions, and displays of stereotypic behaviors, interests and activities. Twin and family studies have indicated a robust role of genetic factors in the dev...

journal_title：Progress in neuro-psychopharmacology & biological psychiatry

authors： Marui T,Koishi S,Funatogawa I,Yamamoto K,Matsumoto H,Hashimoto O,Ishijima M,Nanba E,Nishida H,Sugiyama T,Kasai K,Watanabe K,Kano Y,Kato N,Sasaki T

更新日期：2007-05-09 00:00:00

abstract：:Altered cerebral energy metabolism and mitochondrial dysfunction in periphery and in brain are implicated in the pathophysiology of schizophrenia. This study investigated whether cerebral glucose metabolism (rCGM) abnormalities are linked to altered mitochondrial complex I activity in the periphery, in schizophrenia. ...

journal_title：Progress in neuro-psychopharmacology & biological psychiatry

authors： Ben-Shachar D,Bonne O,Chisin R,Klein E,Lester H,Aharon-Peretz J,Yona I,Freedman N

更新日期：2007-05-09 00:00:00

abstract：OBJECTIVE:To investigate (i) the association between four serotonergic polymorphisms (A-1438G and T102C of the 5-HT2A receptor gene, and 5-HTT VNTR and 5-HTTLPR of the 5-HT transporter gene) and schizophrenia and (ii) the potential interaction of those polymorphisms in the development of schizophrenia. SUBJECTS AND ME...

journal_title：Progress in neuro-psychopharmacology & biological psychiatry

authors： Sáiz PA,García-Portilla MP,Arango C,Morales B,Alvarez V,Coto E,Fernández JM,Bascarán MT,Bousoño M,Bobes J

更新日期：2007-04-13 00:00:00

abstract：BACKGROUND:Gene expressions of the peripheral leukocytes in depressive patients might reflect the systemic dysfunction of major depression. We determined mRNA expression levels of Histone deacetylase 5 (HDAC5) gene and cyclic AMP response element-binding protein 1 (CREB) gene in the leukocyte of depressive patients. HD...

journal_title：Progress in neuro-psychopharmacology & biological psychiatry

authors： Iga J,Ueno S,Yamauchi K,Numata S,Kinouchi S,Tayoshi-Shibuya S,Song H,Ohmori T

更新日期：2007-04-13 00:00:00

abstract：BACKGROUND:Oral naltrexone is an approved treatment for opioid dependence. However, the impact of sustained release naltrexone on the mental health of treated opioid users has not been studied. AIMS:To assess if naltrexone via implant treatment was associated with any change in (i) risk, (ii) rate, and (iii) duration ...

journal_title：Progress in neuro-psychopharmacology & biological psychiatry

authors： Ngo HT,Tait RJ,Arnold-Reed DE,Hulse GK

更新日期：2007-04-13 00:00:00

abstract：:Neuropsychological deficits, such as poor episodic memory, are consistent features of mild cognitive impairment and also that of early stage of dementia. The aim of the present study was to detect cognitive dysfunction among patients with Alzheimer's disease or with mild cognitive impairment (MCI), which refers to a t...

journal_title：Progress in neuro-psychopharmacology & biological psychiatry

authors： Egerházi A,Berecz R,Bartók E,Degrell I

更新日期：2007-04-13 00:00:00

abstract：OBJECTIVE:The aim of this study was to investigate whether augmentation of clozapine with aripiprazole improves clinically significant residual symptoms in stabilized outpatients with chronic schizophrenia. METHODS:Twenty seven stabilized outpatients meeting criteria for chronic schizophrenia, who had residual symptom...

journal_title：Progress in neuro-psychopharmacology & biological psychiatry

authors： Mitsonis CI,Dimopoulos NP,Mitropoulos PA,Kararizou EG,Katsa AN,Tsakiris FE,Katsanou MN

更新日期：2007-03-30 00:00:00

abstract：:Depression is one of the most common neuropsychiatric conditions, with a lifetime prevalence approaching 17%. Although a variety of pharmaceutical agents is available for the treatment of depression, psychiatrists find that many patients cannot tolerate the side effects, do not respond adequately, or finally lose thei...

journal_title：Progress in neuro-psychopharmacology & biological psychiatry

authors： Akhondzadeh Basti A,Moshiri E,Noorbala AA,Jamshidi AH,Abbasi SH,Akhondzadeh S

更新日期：2007-03-30 00:00:00

abstract：:We have previously shown that acute stress-induced release of norepinephrine (NE) facilitates anxiety-like behavioral responses to stress, such as reduction in open-arm exploration on the elevated-plus maze and in social behavior on the social interaction test. Since these responses represent inhibition of ongoing beh...

journal_title：Progress in neuro-psychopharmacology & biological psychiatry

authors： Bondi CO,Barrera G,Lapiz MD,Bedard T,Mahan A,Morilak DA

更新日期：2007-03-30 00:00:00

abstract：:There is evidence for the involvement of the endocrine system in schizophrenia. This involment was widely investigated in female patients. In the current study, we examined prolactin and estradiol serum levels in hospitalized unmedicated men with first-episode and recurrent schizophrenia and then tested possible corre...

journal_title：Progress in neuro-psychopharmacology & biological psychiatry

authors： Segal M,Avital A,Berstein S,Derevenski A,Sandbank S,Weizman A

更新日期：2007-03-30 00:00:00

abstract：:Post-mortem and in-vivo studies support the hypothesis that astrocytes might be involved in the pathogenesis of schizophrenia. To further substantiate this hypothesis two markers of astroglial activation (myo-inositol, S100B) acquired with independent methods ((1)H-MRS, quantitative immunoassay) were concomitantly mea...

journal_title：Progress in neuro-psychopharmacology & biological psychiatry

authors： Rothermundt M,Ohrmann P,Abel S,Siegmund A,Pedersen A,Ponath G,Suslow T,Peters M,Kaestner F,Heindel W,Arolt V,Pfleiderer B

更新日期：2007-03-30 00:00:00

abstract：:Previously, we have shown that orally administered topiramate, a sulfamate-substituted fructopyranose derivative, appears to accentuate rather than diminish some aspects of methamphetamine-induced positive subjective mood and cognitive performance. One possible mechanism by which this might occur would be for topirama...

journal_title：Progress in neuro-psychopharmacology & biological psychiatry

authors： Johnson BA,Wells LT,Roache JD,Wallace CL,Ait-Daoud N,Dawes MA,Liu L,Wang XQ,Javors MA

更新日期：2007-03-30 00:00:00

abstract：PURPOSE:Only a few studies have commented on the use of atypical antipsychotics for the treatment of Borderline Personality Disorder (BPD) features, including affective dysregulation and aggression. We aimed at evaluating both efficacy and safety of quetiapine in a sample of consecutive BPD patients. GENERAL METHODS:2...

journal_title：Progress in neuro-psychopharmacology & biological psychiatry

authors： Perrella C,Carrus D,Costa E,Schifano F

更新日期：2007-01-30 00:00:00

abstract：OBJECTIVES:The objectives of this study were: (1) to investigate, in a clinical practice setting, the effectiveness of olanzapine in the treatment of schizophrenia among partially-responding, symptomatic Asian patients who switch from conventional antipsychotic treatment, (2) to assess the safety of olanzapine and (3) ...

journal_title：Progress in neuro-psychopharmacology & biological psychiatry

authors： Lu Z,Hu J,Chen CK,Lan TH,Diokno GL Jr,Lee BY,McElroy H,Harrison G,Ang Q

更新日期：2007-01-30 00:00:00

abstract：:Self-reported behavior and attitudes towards eating [Eating Disorder Inventory-2; Garner DM (1991). Eating Disorder Inventory-2: Professional Manual. Odessa, Fl.: Psychological Assessment Resources; Estonian version Podar I, Hannus A, Allik J (1999). Personality and Affectivity Characteristics Associated With Eating D...

journal_title：Progress in neuro-psychopharmacology & biological psychiatry

authors： Podar I,Jaanisk M,Allik J,Harro J

更新日期：2007-01-30 00:00:00

abstract：:Huntington's disease (HD) is a hereditary disorder clinically characterized by involuntary movements, cognitive decline and psychiatric symptoms. We report on a patient with HD, whose involuntary movements and psychiatric symptoms were clinically improved with perospirone, a second-generation antipsychotic agent with ...

journal_title：Progress in neuro-psychopharmacology & biological psychiatry

authors： Roppongi T,Togo T,Nakamura S,Asami T,Yoshimi A,Shiozaki K,Kato D,Kawanishi C,Hirayasu Y

更新日期：2007-01-30 00:00:00

abstract：:Codeine is metabolized by the cytochrome P450 2D6 (CYP2D6) to morphine. Codeine is a much weaker agonist at mu opioid receptors than morphine. Therefore, codeine analgesia is highly dependent on CYP2D6 activity. Large prospective studies in the clinical environment do not exist, but it appears reasonable to avoid code...

journal_title：Progress in neuro-psychopharmacology & biological psychiatry

authors： Susce MT,Murray-Carmichael E,de Leon J

更新日期：2006-09-30 00:00:00

abstract：BACKGROUND:An abnormality in regional cerebral blood flow (rCBF) in anorexia nervosa (AN) patients has been reported. There are very few studies that have investigated the rCBF changes in the recovery process of AN. METHODS:For eight female AN patients, we performed (123)I-IMP single photon emission computed tomograph...

journal_title：Progress in neuro-psychopharmacology & biological psychiatry

authors： Matsumoto R,Kitabayashi Y,Narumoto J,Wada Y,Okamoto A,Ushijima Y,Yokoyama C,Yamashita T,Takahashi H,Yasuno F,Suhara T,Fukui K

更新日期：2006-09-30 00:00:00

abstract：:This study compared the anti-aggressiveness effects of the atypical anti-psychotic olanzapine with that of selective serotonin reuptake inhibitors (SSRI) and benzodiazepines (BZD) among patients with heroin dependence submitted to opioid-agonists substitution treatment. Sixty-seven (67) patients who met the DSM-IV cri...

journal_title：Progress in neuro-psychopharmacology & biological psychiatry

authors： Gerra G,Di Petta G,D'Amore A,Iannotta P,Bardicchia F,Falorni F,Coacci A,Strepparola G,Campione G,Lucchini A,Vedda G,Serio G,Manzato E,Antonioni M,Bertacca S,Moi G,Zaimovic A

更新日期：2006-09-30 00:00:00

abstract：:It has been shown that small doses of ethanol (

journal_title：Progress in neuro-psychopharmacology & biological psychiatry

authors： Korkosz A,Zatorski P,Taracha E,Plaznik A,Kostowski W,Bienkowski P

更新日期：2006-09-30 00:00:00

abstract：:Sustained attention deficits are proposed to be both state and trait indicators of bipolar disorder. The nature of these deficits and their association with medication and symptoms is not clear yet. The aim of this study was to investigate the impairments in various components of sustained attention task in euthymic a...

journal_title：Progress in neuro-psychopharmacology & biological psychiatry

authors： Bora E,Vahip S,Akdeniz F

更新日期：2006-08-30 00:00:00

abstract：:Glutamatergic hyperactivity hypothesis in obsessive-compulsive disorder (OCD) has been proposed but not tested. Memantine is an uncompetitive N-methyl-d-aspartate (NMDA) receptor antagonist. We report two cases of refractory obsessive-compulsive disorder treated with an augmentation of memantine at 15 mg/day. The firs...

journal_title：Progress in neuro-psychopharmacology & biological psychiatry

authors： Pasquini M,Biondi M

更新日期：2006-08-30 00:00:00

abstract：:Despite the increasing recognition of attention-deficit hyperactivity disorder (ADHD) in adults, there is a paucity of controlled pharmacological trials. Recent reports have suggested the potential usefulness of mood stabilizing drugs for ADHD. To this end, the authors completed a pilot study with oxcarbazepine for th...

journal_title：Progress in neuro-psychopharmacology & biological psychiatry

authors： Davids E,Kis B,Specka M,Gastpar M

更新日期：2006-08-30 00:00:00

abstract：UNLABELLED:Schizophrenia-specific alterations in the densities of interneurons immunoreactive (ir) to the calcium binding proteins are reported for several cortical regions. However, no reported studies have searched for such differences within the posterior cingulate cortex using antibodies to a specific calcium bindi...

journal_title：Progress in neuro-psychopharmacology & biological psychiatry

authors： Wheeler DG,Dixon G,Harper CG

更新日期：2006-06-01 00:00:00

abstract：:Preliminary evidence revealed a decrease of regional cerebral blood flow in the thalamus and basal ganglia contralateral to the deficit and suggested that hysterical conversion deficits might entail a functional disorder in striatothalamocortical circuits. However, there is no systematic structural magnetic resonance ...

journal_title：Progress in neuro-psychopharmacology & biological psychiatry

authors： Atmaca M,Aydin A,Tezcan E,Poyraz AK,Kara B

更新日期：2006-06-01 00:00:00

abstract：:In the preset study, the authors investigated that effects of the antipsychotic drug risperidone on psychotic depression and examined the mechanism of risperidone to ameliorate psychotic depression. Fifteen patients met the DSM-IV criteria for major depressive disorder with psychotic features and the remaining five pa...

journal_title：Progress in neuro-psychopharmacology & biological psychiatry

authors： Goto M,Yoshimura R,Kakihara S,Shinkai K,Yamada Y,Kaji K,Ueda N,Nakamura J

更新日期：2006-06-01 00:00:00

abstract：:Delayed carbon monoxide (CO) encephalopathy is a serious complication of acute CO poisoning. We present a case of successful treatment of ziprasidone, a newer atypical antipsychotic, in delayed CO encephalopathy. A 52-year-old depressed woman suffered acute CO intoxication after an attempt of suicide by burning charco...

journal_title：Progress in neuro-psychopharmacology & biological psychiatry

authors： Hu MC,Shiah IS,Yeh CB,Chen HK,Chen CK

更新日期：2006-06-01 00:00:00

abstract：:Citalopram, a selective serotonin reuptake inhibitor (SSRI), has been used as a neuroendocrine probe to assess serotonin (5-HT) function in human subjects. In an effort to characterize the oral citalopram challenge, we hypothesized that oral racemic citalopram would increase plasma cortisol, prolactin and adrenocortic...

journal_title：Progress in neuro-psychopharmacology & biological psychiatry

authors： Hawken ER,Owen JA,Van Vugt D,Delva NJ

更新日期：2006-06-01 00:00:00

abstract：:Hyperprolactinemia can be induced by dopamine D2 receptor-binding drugs such as antipsychotic drugs. The author investigated the relationship between changes in prolactin (PRL) and clinical efficacy of risperidone. In this study, 27 acute psychotic inpatients completed a 12-week trial of risperidone. At baseline and a...

journal_title：Progress in neuro-psychopharmacology & biological psychiatry

authors： Lee BH,Kim YK

更新日期：2006-06-01 00:00:00

abstract：:The authors investigated the impact of the CYP2D6 genotypes on the plasma concentration of paroxetine (PAX) in 55 Japanese psychiatric patients. They were administered 10 to 40 mg/day (24+/-10.0 mg/day) of PAX and maintained at the same daily dose for at least two weeks to obtain the steady-state concentrations. The p...

journal_title：Progress in neuro-psychopharmacology & biological psychiatry

authors： Ueda M,Hirokane G,Morita S,Okawa M,Watanabe T,Akiyama K,Shimoda K

更新日期：2006-05-01 00:00:00

abstract：:There is strong evidence that oxygen free radicals may play an important role in the pathophysiology of schizophrenia. Impaired antioxidant defense and increased lipid peroxidation have been previously reported in drug-naïve, first episode and chronically medicated schizophrenic patients using typical neuroleptics. We...

journal_title：Progress in neuro-psychopharmacology & biological psychiatry

authors： Gama CS,Salvador M,Andreazza AC,Kapczinski F,Silva Belmonte-de-Abreu P

更新日期：2006-05-01 00:00:00

abstract：:Effects of acute and chronic tianeptine treatments on ethanol withdrawal syndrome were investigated in rats. Ethanol (7.2% v/v) was given to adult male Wistar rats by a liquid diet for 30 days. Acute or chronic (twice daily) tianeptine (5, 10 and 20 mg/kg) and saline were administered to rats intraperitoneally. Acute ...

journal_title：Progress in neuro-psychopharmacology & biological psychiatry

authors： Uzbay T,Kayir H,Celik T,Yüksel N

更新日期：2006-05-01 00:00:00

abstract：:Several studies have shown that olanzapine is effective in weight restoration and maintenance for patients with anorexia nervosa (AN). However, major depression is a very common comorbid psychiatric disorder associated with AN. Additional antidepressant therapy may be required for treating anorexic patients with major...

journal_title：Progress in neuro-psychopharmacology & biological psychiatry

authors： Wang TS,Chou YH,Shiah IS

更新日期：2006-03-01 00:00:00

abstract：:The present study compared retrospectively in a clinical non-experimental setting the efficacy of buprenorphine (BUP) in different subgroups of dually diagnosed and non-dually diagnosed opioid-dependent patients: all the subjects included in the study showed severe long-lasting heroin addiction and 68.4% were affected...

journal_title：Progress in neuro-psychopharmacology & biological psychiatry

authors： Gerra G,Leonardi C,D'Amore A,Strepparola G,Fagetti R,Assi C,Zaimovic A,Lucchini A

更新日期：2006-03-01 00:00:00

abstract：:The newer, atypical antipsychotic drugs have improved the treatment of schizophrenia and are widely used. A disadvantage is that they increase food intake, promote weight gain and may facilitate development of diabetes. The mechanism of the latter effect is controversial. A possible interaction of these drugs with glu...

journal_title：Progress in neuro-psychopharmacology & biological psychiatry

authors： Robinson KA,Yacoub Wasef SZ,Buse MG

更新日期：2006-01-01 00:00:00

abstract：:Most antipsychotics were thought to induce antipsychotic action at an excess of 70% striatal dopamine D2 receptor occupancy, while the clinical dose of clozapine was reported to show less than 60% occupancy. High-dose clozapine could occupy as high as 80% of striatal dopamine D2 receptor in monkey PET studies. Althoug...

journal_title：Progress in neuro-psychopharmacology & biological psychiatry

authors： Takano A,Suhara T,Kusumi I,Takahashi Y,Asai Y,Yasuno F,Ichimiya T,Inoue M,Sudo Y,Koyama T

更新日期：2006-01-01 00:00:00

abstract：:The Wistar Kyoto (WKY) rat has been proposed as an animal model of depressive behavior. Exposing WKY rats to stress stimulation produces symptoms such as anhedonia, psychomotor retardation, ambivalence and negative memory bias. Given the role of the mesolimbic dopamine (DA) system in cognitive, emotional and motivatio...

journal_title：Progress in neuro-psychopharmacology & biological psychiatry

authors： Jiao X,Paré WP,Tejani-Butt SM

更新日期：2006-01-01 00:00:00

abstract：:Nutrition is one of the critical factors insuring adequate growth and development in all species. In particular, brain development is sensitive to specific nutrient intake such as proteins and lipids, which are important for cell membrane formation and myelinization. Carbohydrate intake insures adequate short-term ene...

journal_title：Progress in neuro-psychopharmacology & biological psychiatry

authors： Walker CD

更新日期：2005-12-01 00:00:00

abstract：:Schizophrenic patients generally appear to have a disturbed single-carbon metabolism. Methionine and homocysteine are intermediary metabolites in this metabolic system. In a case-control study of the cerebrospinal fluid, a majority of the patients had elevated methionine and a smaller subgroup had elevated homocystein...

journal_title：Progress in neuro-psychopharmacology & biological psychiatry

authors： Regland B

更新日期：2005-09-01 00:00:00